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CRP (C-Reactive Protein) Test
✅ Up to date🔬 Evidence: StrongInternal Medicine
Diğer adları: C-reactive protein, CRP level, High-sensitivity CRP
⚠️
Discuss your test results with your doctor. This page is for informational purposes only and does not provide a diagnosis.
⚡ Key Facts
• A protein produced by the liver in response to inflammation, infection, and tissue damage
• Non-specific — may rise in many different conditions
• Standard CRP evaluates acute inflammation; hs-CRP assesses low-grade chronic inflammation and cardiovascular risk
• Normal standard CRP: <5 mg/L
🧪 What Does This Test Measure?
The CRP test measures C-reactive protein, produced by the liver in response to inflammation, infection, and tissue damage throughout the body.
📋 Why Is It Ordered?
Ordered for infection and inflammation evaluation, monitoring treatment response, autoimmune disease follow-up, and cardiovascular risk assessment (hs-CRP).
🔧 Preparation
CRP testing generally requires no special preparation. Fasting is not required.
📊 Reference Ranges
Standard CRP:
Normal: <5 mg/L (some labs: <10 mg/L)
Mild: 10–40 mg/L
Moderate: 40–200 mg/L
Severe: >200 mg/L
hs-CRP (cardiovascular risk):
<1 mg/L: low risk
1–3 mg/L: moderate risk
>3 mg/L: higher risk
⬆️ High Values
Elevated CRP may be associated with bacterial infection, autoimmune disease, tissue damage, or postoperative inflammation. Mild elevations may be associated with obesity, smoking, or chronic conditions.
⬇️ Low Values
Low CRP generally suggests the absence of active inflammation or infection. Low hs-CRP is considered favorable for cardiovascular risk.
⚙️ What Can Affect Results?
Obesity, smoking, medications, physical activity, sleep quality, and acute infections are key factors that may affect CRP results.
🔬 Evidence Summary
Strong evidence: 2 guidelines, 1 meta-analysis, 1 clinical trial (RCT), 3 reviews.
✅ Key Takeaways
💡
What you learned: CRP is a non-specific marker of inflammation and infection; an elevated result does not establish a diagnosis on its own. Standard CRP is used for acute conditions; hs-CRP is used for cardiovascular risk assessment.
⛔
A CRP result alone cannot diagnose infection, inflammation, or heart disease. Clinical context and supporting tests are needed.
🔬 Sources Used on This Page
8 sources · Most recent publication: 2024📋
Guideline
Expert society and guideline recommendations
2
sources
📊
Systematic review / meta-analysis
Combined analysis of multiple studies
1
source
🔬
Clinical trial (RCT)
Controlled research conducted in humans
1
source
📖
Review
Comprehensive topic evaluation
4
sources
Overall assessment: Evidence level for this topic is strong. This page is supported by 2 guidelines, 1 systematic review/meta-analysis, 1 clinical trial, 4 reviews.
📝 Questions to Ask Your Doctor
Be prepared for your appointment. Add questions to your list.
Last reviewed: 3/26/2026
Next review: 6/26/2026
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⚖️ This page does not replace medical advice. Make treatment decisions with your doctor.
Content is based on scientific studies indexed in PubMed and current clinical guidelines.
Content is based on scientific studies indexed in PubMed and current clinical guidelines.