Home → Tests → eGFR
eGFR (Estimated Glomerular Filtration Rate)
✅ Up to date🔬 Evidence: ModerateInternal Medicine
Diğer adları: GFR, Glomerular filtration rate, Kidney filtration rate
⚠️
Discuss your test results with your doctor. This page is for informational purposes only and does not provide a diagnosis.
⚡ Key Facts
• A calculated value that estimates how well the kidneys filter blood per minute
• Not a directly measured test — calculated from creatinine, age, and sex
• ≥60 mL/min/1.73 m² is generally considered adequate
• Used for CKD staging alongside albuminuria
🧪 What Does This Test Measure?
eGFR is a calculated value that estimates how well the kidneys filter blood per minute, derived from creatinine level, age, and sex using standardized formulas.
📋 Why Is It Ordered?
Ordered for kidney function evaluation, CKD staging, medication dose adjustment, risk assessment, and kidney disease monitoring.
🔧 Preparation
eGFR is not a direct test — it is calculated from a blood creatinine test. Therefore, preparation requirements for creatinine measurement apply.
📊 Reference Ranges
KDIGO CKD stages (eGFR, mL/min/1.73 m²):
G1: ≥90 — Normal or high
G2: 60–89 — Mildly decreased
G3a: 45–59 — Mild to moderate decrease
G3b: 30–44 — Moderate to severe decrease
G4: 15–29 — Severely decreased
G5: <15 — Kidney failure
⬆️ High Values
High eGFR generally indicates good kidney function. Physiological elevation occurs in pregnancy. In some cases, it may be associated with hyperfiltration.
⬇️ Low Values
Low eGFR may be associated with decreased kidney function. Chronic kidney disease, acute kidney injury, dehydration, or certain medications may contribute.
⚙️ What Can Affect Results?
Factors affecting eGFR are related to creatinine measurement: muscle mass, age, sex, diet, medications, and hydration. The formula used also matters.
🔬 Evidence Summary
Moderate evidence: 1 guideline, 2 landmark observational studies.
✅ Key Takeaways
💡
What you learned: eGFR is the most widely used indicator of kidney function. ≥60 mL/min/1.73 m² generally indicates adequate function; lower values are evaluated alongside albuminuria and clinical context.
⛔
A single eGFR value cannot diagnose kidney disease. Chronicity (≥3 months), albuminuria, and clinical context are needed.
🔬 Sources Used on This Page
3 sources · Most recent publication: 2024📋
Guideline
Expert society and guideline recommendations
1
source
👁
Observational
Observational and cohort studies
2
sources
Overall assessment: Evidence level for this topic is moderate. This page is supported by 1 guideline, 2 observational studies.
📝 Questions to Ask Your Doctor
Be prepared for your appointment. Add questions to your list.
Last reviewed: 4/1/2026
Next review: 7/1/2026
⚖️ Comparisons
🔗 Related Topics
🩺 Chronic kidney disease🧪 Kreatinin (eGFR girdisi)🧪 Üre (BUN)🧪 Açlık kan şekeri (diyabetik nefropati bağlamı)
⚖️ This page does not replace medical advice. Make treatment decisions with your doctor.
Content is based on scientific studies indexed in PubMed and current clinical guidelines.
Content is based on scientific studies indexed in PubMed and current clinical guidelines.