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OGTT (Oral Glucose Tolerance Test)
✅ Up to date🔬 Evidence: StrongEndocrine & Metabolism
Diğer adları: 75g glucose test, Glucose tolerance test, GTT
⚠️
Discuss your test results with your doctor. This page is for informational purposes only and does not provide a diagnosis.
⚡ Key Facts
• Measures blood sugar 2 hours after ingesting 75 grams of glucose
• One of the most sensitive tests for diabetes and prediabetes assessment
• Normal 2-hour: <140 mg/dL | Prediabetes: 140–199 mg/dL | Diabetes: ≥200 mg/dL
• Also used in gestational diabetes screening
🧪 What Does This Test Measure?
The OGTT measures how well the body regulates blood sugar after ingesting a standardized 75-gram glucose solution, assessed at the 2-hour mark.
📋 Why Is It Ordered?
Ordered for diabetes and prediabetes assessment, gestational diabetes screening, and when fasting glucose or HbA1c results are borderline.
🔧 Preparation
Several days of normal diet and 8–14 hours of fasting are required before the test. The test is typically done in the morning and takes approximately 2 hours.
📊 Reference Ranges
Normal 2-hour: <140 mg/dL (<7.8 mmol/L)
Prediabetes (IGT): 140–199 mg/dL (7.8–11.0 mmol/L)
Diabetes: ≥200 mg/dL (≥11.1 mmol/L)
⚠️ Thresholds may vary by guideline and laboratory.
⬆️ High Values
Elevated OGTT may be associated with diabetes, prediabetes (IGT), gestational diabetes, or insulin resistance. Stress and certain medications may also affect results.
⬇️ Low Values
Excessively low blood sugar during OGTT is rare but may be significant. It may be associated with reactive hypoglycemia or certain hormonal/gastrointestinal conditions.
⚙️ What Can Affect Results?
Diet preparation, fasting duration, physical activity, stress, medications, and test conditions can significantly affect OGTT results.
🔬 Evidence Summary
Strong evidence: 3 guidelines, 2 systematic reviews, 1 clinical trial, and supporting observational/review studies.
✅ Key Takeaways
💡
What you learned: OGTT evaluates how your body handles glucose over time. A 2-hour result below 140 mg/dL is considered normal.
⛔
A single OGTT result cannot establish a diagnosis on its own. Clinical context and confirmatory testing are needed.
🔬 Sources Used on This Page
10 sources · Most recent publication: 2025📋
Guideline
Expert society and guideline recommendations
3
sources
📊
Systematic review / meta-analysis
Combined analysis of multiple studies
2
sources
🔬
Clinical trial (RCT)
Controlled research conducted in humans
1
source
📖
Review
Comprehensive topic evaluation
2
sources
👁
Observational
Observational and cohort studies
2
sources
Overall assessment: Evidence level for this topic is strong. This page is supported by 3 guidelines, 2 systematic reviews/meta-analysis, 1 clinical trial, 2 reviews, 2 observational studies.
📝 Questions to Ask Your Doctor
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Last reviewed: 3/25/2026
Next review: 6/25/2026
🔗 Related Topics
🩺 Type 2 diabetes🩺 Gestasyonel diyabet🧪 Açlık Kan Şekeri (AKŞ)🧪 HbA1c (Glycated hemoglobin)🧪 Fasting insulin🧪 HOMA-IR
⚖️ This page does not replace medical advice. Make treatment decisions with your doctor.
Content is based on scientific studies indexed in PubMed and current clinical guidelines.
Content is based on scientific studies indexed in PubMed and current clinical guidelines.