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NLR (Neutrophil-to-Lymphocyte Ratio)
✅ Up to date🔬 Evidence: LimitedInternal Medicine
Diğer adları: Neutrophil lymphocyte ratio, Neutrophil-to-lymphocyte ratio
⚠️
Discuss your test results with your doctor. This page is for informational purposes only and does not provide a diagnosis.
⚡ Key Facts
• A ratio calculated by dividing neutrophil count by lymphocyte count
• Reflects the balance between innate and adaptive immunity
• No internationally standardized threshold exists
• Used as a supplementary inflammation and prognosis marker
🧪 What Does This Test Measure?
The NLR (neutrophil-to-lymphocyte ratio) is calculated by dividing neutrophil count by lymphocyte count, reflecting the balance between innate and adaptive immunity.
📋 Why Is It Ordered?
Used for inflammation severity assessment, infection monitoring, oncology prognosis, and cardiovascular risk evaluation as a supplementary marker.
🔧 Preparation
NLR is not a separate test — it is calculated from the CBC differential. No special preparation beyond CBC requirements.
📊 Reference Ranges
No internationally standardized threshold. Commonly cited approximate values:
Normal: 1–3
Elevated: >3 (may indicate inflammation or stress)
High: >6 (significant inflammatory or stress response)
⬆️ High Values
Elevated NLR may be associated with infection, inflammation, physiological stress, surgery, and certain oncological conditions.
⬇️ Low Values
Low NLR is generally not considered clinically significant. It may reflect neutropenia or relative lymphocytosis.
⚙️ What Can Affect Results?
Corticosteroids, infection, stress, age, exercise, smoking, and individual variation in neutrophil/lymphocyte counts may affect NLR.
🔬 Evidence Summary
Limited evidence: 3 reviews and 1 observational study.
✅ Key Takeaways
💡
What you learned: NLR is a supplementary inflammation marker. It has no standardized threshold and should be interpreted alongside clinical context.
⛔
NLR alone cannot diagnose any condition. It is a supplementary marker interpreted alongside clinical findings.
🔬 Sources Used on This Page
4 sources · Most recent publication: 2024📖
Review
Comprehensive topic evaluation
3
sources
👁
Observational
Observational and cohort studies
1
source
Overall assessment: Evidence level for this topic is limited. This page is supported by 3 reviews, 1 observational study.
📝 Questions to Ask Your Doctor
Be prepared for your appointment. Add questions to your list.
Last reviewed: 4/2/2026
Next review: 7/2/2026
🔗 Related Topics
🧪 Nötrofil (NLR'nin payı)🧪 Lenfosit (NLR'nin paydası)🧪 Lökosit / WBC (total beyaz küre)🧪 CRP (C-reaktif protein)🧪 Prokalsitonin (bakteriyel enfeksiyon belirteci)
⚖️ This page does not replace medical advice. Make treatment decisions with your doctor.
Content is based on scientific studies indexed in PubMed and current clinical guidelines.
Content is based on scientific studies indexed in PubMed and current clinical guidelines.